*Neoadjuvant treatment may be used in selected cases with cT1cN0

AC = Doxorubicin + Cyclophosphamide; EC = Epirubicin + Cyclophosphamide; H = Trastuzumab; P = Pertuzumab; PTX = Paclitaxel; T-DM1 = Trastuzumab emtansine; T-DXd = Trastuzumab deruxtecan; T = Docetaxel; wPTX = Weekly Paclitaxel